Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
Blog Article
one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the cure of several myeloma. Its synthesis or research is crucial for making sure the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets distinct varieties of most cancers, like chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers for instance breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is important for optimizing the creation process and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is made use of to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug helpful in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment of colorectal cancer and tiny mobile lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): CAS NO.154229-19-3 This compound is linked to the synthesis of adamantane derivatives, that have many applications, which includes antiviral Houses.
Vildagliptin Intermediates: Employed in the manufacture of vildagliptin, an oral drug for form two diabetic issues that inhibits the enzyme DPP-4 to manage blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which are Employed in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate OTAVA-BB1207229 2: A precursor within the synthesis of canagliflozin, a medication utilized to manage type two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).